Zoster immunoglobulin (ZIG)

160 mg/mL immunoglobulin (mainly IgG) prepared from human plasma containing high levels of antibody to varicella-zoster virus. 

Single vials containing 200 IU of varicella-zoster antibody, with the actual volume stated on the label on the vial. 

Also contains glycine.

People must receive ZIG within 96 hours of exposure. However, ZIG may have some efficacy if given as late as 10 days after exposure. ZIG can prevent or ameliorate varicella in:

• infants <1 month of age
• children who are being treated with immunosuppressive therapy
• pregnant women