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Table. Accelerated hepatitis B vaccination schedules for people with imminent risk of exposure

Vaccine Age of vaccine recipient (years) Dose (hepatitis B surface antigen protein) Number of doses Recommended schedule minimum interval
Engerix-B (paediatric formulation) <20 10 μg 4
  • 1st dose: day 0 (day of vaccination)
  • 2nd dose: 4 weeks after 1st dose
  • 3rd dose: 8 weeks after 1st dose
  • 4th dose: 12 months after 1st dose
Engerix-B (adult formulation) ≥20 20 μg 4
  • 1st dose: day 0 (day of vaccination)
  • 2nd dose: 4 weeks after 1st dose
  • 3rd dose: 8 weeks after 1st dose
  • 4th dose: 12 months after 1st dose

or

  • 1st dose: day 0 (day of vaccination)
  • 2nd dose: 7 days after 1st dose
  • 3rd dose: 3 weeks after 1st dose
  • 4th dose: 12 months after 1st dose
Twinrix (720/20) ≥16 20 μg 4
  • 1st dose: day 0 (day of vaccination)
  • 2nd dose: 7 days after 1st dose
  • 3rd dose: 3 weeks after 1st dose
  • 4th dose: 12 months after 1st dose
Related diseases
Hepatitis B

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