People at risk of exposure to mpox are recommended to receive mpox vaccine
Mpox vaccine in a 2-dose schedule is recommended for groups at risk of exposure to mpox, as detailed below. People in these risk groups who are severely immunocompromised should be prioritised to receive the 2nd dose of mpox vaccine as close to (but not before) 28 days after the 1st dose as possible as part of the primary preventive vaccination (PPV) schedule.
Gay, bisexual or other men who have sex with men (GBMSM)
Gay, bisexual or other men who have sex with men (GBMSM)
PPV with mpox vaccine is recommended for GBMSM, including transgender and gender-diverse people.
Sex workers
Sex workers
PPV with mpox vaccine is recommended for sex workers, particularly those whose clients may be at risk of mpox exposure.
People with HIV
People with HIV
PPV with mpox vaccine is recommended for people with HIV or other causes of immune suppression, if they report risk of exposure to mpox. Particular consideration should be given to those with known CD4 count <200 cells/mm3.
The details of dosage and administration are outlined in Vaccines, dosage and administration.
Other individuals whose sexual networks might include GBMSM
Other individuals whose sexual networks might include GBMSM
PPV with mpox vaccine is recommended for any other individuals who may be involved in the sexual networks of GBMSM, including transgender and gender-diverse people.
The details of dosage and administration are outlined in Vaccines, dosage and administration.
Booster dose
Booster dose
People who have previously received a smallpox vaccine are likely to have some residual protection, however, may benefit from receiving a dose of mpox vaccine.
If a person who is recommended to receive PPV for mpox has had a smallpox vaccine in the past, 1 additional dose of mpox vaccine is recommended if the previous dose of a smallpox vaccine was given more than 10 years ago.