People with developmental disabilities who attend either residential or non-residential daycare facilities are recommended to receive hepatitis B vaccine. This is because of the high prevalence of markers indicating past or current infection in people in these settings, including a prevalence of hepatitis B surface antigen of >10%.16-18
The combination hepatitis A-hepatitis B vaccine may be appropriate for people with developmental disabilities if they are not immune to either disease. This is because they have an increased risk of both conditions. This is usually given in 3 doses using Twinrix (720/20). See Table. Combination hepatitis A-hepatitis B vaccines in Vaccines, dosage and administration.