Susceptible sexual partners of people who are positive for hepatitis B surface antigen are recommended to receive post-exposure hepatitis B immunoglobulin (HBIG) and hepatitis B vaccination.

Both the vaccine course and HBIG should start within 14 days of the last sexual contact. See Public health management and Table. Post-exposure prophylaxis for non-immune people exposed to a source that is positive for hepatitis B surface antigen.

Susceptible clients of sexual health services are recommended to receive hepatitis B vaccine when they first attend the service. This is because hepatitis B is relatively common in clients of sexual health services.

Adult-formulation hepatitis B vaccine should be given in a 3-dose schedule. See Table. Monovalent hepatitis B vaccines for adolescents and adults in Vaccines, dosage and administration.

Levels of antibody to hepatitis B surface antigen should be checked after the vaccination course. See Serological testing after hepatitis B vaccination.

Page history

Last updated: 
4 June 2018
Last reviewed: 
4 June 2018


hepatitis B immunoglobulin