Unless a woman is otherwise eligible, a dose of COVID-19 vaccine is not routinely recommended in pregnancy. Pregnant women who have previously been vaccinated can discuss with their healthcare provider whether to have a further dose during their pregnancy, based on an individual risk-benefit assessment. The risk of severe disease from Omicron infection has been shown to be low in pregnant women who have been previously vaccinated.2,3 A dose during pregnancy may reduce the risk of severe COVID-19 in young infants through transplacental passage of antibodies.4-6
Omicron XBB.1.5-based vaccines are preferred in pregnancy. Although the latest mRNA COVID-19 vaccines have not been formally studied in pregnant women, ATAGI considers them suitable and safe for use.