Overseas scenario

Rabies vaccine schedule in Australia

HRIG category III terrestrial animal exposures, and category II and III bat exposures only

Person received nerve tissue–derived rabies vaccine.

Restart schedule, starting at day 0.

  • Administer HRIG if no RIG already given and within 7 days of receipt of 1st PEP vaccine dose.
  • Do not give HRIG if more than 7 days since 1st dose of vaccine (day 0).

Use of vaccine or RIG is unsure or unknown, or documentation is poor.

Restart schedule, starting at day 0.

  • Administer HRIG if no RIG already given and within 7 days of receipt of 1st PEP vaccine dose.
  • Do not give HRIG if more than 7 days since 1st dose of vaccine (day 0).

Scenario is well documented, RIG (equine or human) was given, plus vaccine given either intramuscularly or intradermally.

Align with nearest due dose and resume schedule. Administer vaccine intramuscularly (intramuscularly or subcutaneously if human diploid cell vaccine used).

  • No HRIG is needed.

Person received 2 vaccine doses intramuscularly on day 0. RIG (equine or human) may or may not have been administered at same time as 1st dose of vaccine.

Give a further dose on day 7 and day 21 (Zagreb regimen).

  • Administer HRIG if no RIG already given and within 7 days of receipt of 1st PEP vaccine dose.
  • Do not give HRIG if more than 7 days since 1st dose of vaccine (day 0).

Person is immunocompromised, and vaccines were administered intradermally.

Regardless of number of previous doses, give a 5-dose schedule intramuscularly (intramuscularly or subcutaneously if human diploid cell vaccine used). Check serology 2–4 weeks after final dose (see Serological testing following rabies vaccination).

  • Administer HRIG if no RIG already given and within 7 days of receipt of 1st PEP vaccine dose.
  • Do not give HRIG if more than 7 days since 1st dose of vaccine (day 0).

HRIG = human rabies immunoglobulin; PEP = post-exposure prophylaxis; RIG= rabies immunoglobulin

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Last updated: 
7 June 2018
Last reviewed: 
7 June 2018

Definitions

HRIG
human rabies immunoglobulin
RIG
rabies immunoglobulin
PEP
post-exposure prophylaxis