Age or immune status

Has received 0 doses of MMR vaccine, or unknown

Has received 1 dose of MMR vaccine

Has received 2 doses of MMR vaccine

Immunocompromised (any age)

Give normal human immunoglobulin (NHIG) — 0.5 mL/kg to maximum of 15 mL

Give NHIG — 0.5 mL/kg to maximum of 15 mL

Give NHIG — 0.5 mL/kg to maximum of 15 mL

Birth to 5 months

Give NHIG — 0.2 mL/kg, only if either:

  • the mother has had <2 doses of MMR vaccine and no history of past measles infection, or
  • the mother is negative for measles IgG

Not applicable

Not applicable

6–11 months

  • Give MMR vaccine now, then repeat dose at 12 months of age or 4 weeks later (whichever is later).
  • Give MMRV vaccine at 18 months of age, with a minimum interval of 4 weeks after the previous dose of MMR vaccine (see Recommendations).

Not applicable

Not applicable

12 months to <18 months

  • Give MMR vaccine now.
  • Give MMRV vaccine at 18 months of age, with a minimum interval of 4 weeks after the previous dose of MMR vaccine (see Recommendations

Give MMRV vaccine, or MMR if already immunised against varicella, at least 4 weeks after the previous dose of MMR vaccine.

Not necessary

≥18 months, or born during or since 1966, and not pregnant

  • Give MMR vaccine now.
  • Give a subsequent dose of MMR or MMRV vaccine at least 4 weeks after the 1st valid dose (a valid dose is one given at ≥12 months of age) to complete a 2-dose vaccine schedule (see Recommendations).
  • In children aged ≥4 to <14 years, MMRV vaccine could be used as the 1st dose if the child has not already received a varicella-containing vaccine (see Recommendations)

Give MMR or MMRV vaccine (based on age).

Not necessary

Pregnant

  • If time, check IgG
  • Give NHIG — 0.2 mL/kg to maximum of 15 mL
  • Consult public health authority (and/or obstetrician or general practitioner) about interpreting IgG results and using NHIG.
  • If time, check IgG.
  • Give NHIG — 0.2 mL/kg to maximum of 15 mL.
  • Consult public health authority (and/or obstetrician or general practitioner) about interpreting IgG results and using NHIG.

Not necessary

MMR = measles-mumps-rubella; MMRV = measles-mumps-rubella-varicella; NHIG = normal human immunoglobulin

Source: Adapted from the Communicable Diseases Network Australia national guidelines for measles2

Last updated: 
12 April 2019
Last reviewed: 
12 April 2019

Definitions

MMR
measles-mumps-rubella
NHIG
normal human immunoglobulin
MMRV
measles-mumps-rubella-varicella