Table. Recommendations for revaccination after haematopoietic stem cell transplant in children and adults
These recommendations are regardless of previous vaccination history. Young children may need extra doses of certain vaccines in addition to those in this table. Young children should complete the recommended age-based vaccination schedule after completing the primary post-HSCT vaccination doses in this table. See the relevant disease-specific chapters in this Handbook for details.
Vaccine |
6 months after HSCT |
8 months after HSCT |
12 months after HSCT |
24 months after HSCT |
Comments |
---|---|---|---|---|---|
DTPa (diphtheria-tetanus-pertussis)–containing vaccine for children <10 years of age and dTpa for those ≥10 years of age |
Yes |
Yes |
Yes |
Not needed
|
|
Hib (Haemophilus influenzae type b) vaccine |
Yes |
Yes |
Yes |
Not needed |
|
Hepatitis B vaccine |
Yes |
Yes |
Yes |
Not needed |
|
9vHPV (9-valent human papillomavirus vaccine |
No |
Yes |
Yes (see comments) |
Yes (see comments) |
|
IPV (inactivated poliovirus) vaccine |
Yes |
Yes |
Yes |
Not needed |
|
Influenza vaccine |
Yes (2 doses in 1st year after transplant, then 1 dose every year after that) |
Yes (if not received already) |
Yes (if not received already) |
Yes |
|
MMR (measles-mumps-rubella) vaccine |
No |
No |
No |
Yes (1 or 2 doses with a minimum interval of 4 weeks; see comments) |
|
MenB (meningococcal B) vaccine |
Yes |
Yes |
Not needed (see comments) |
Not needed (see comment) |
|
MenACWY (quadrivalent meningococcal conjugate) vaccine |
Yes |
Yes |
Not needed (see comments) |
Not needed (see comment) |
|
13vPCV (13-valent pneumococcal conjugate vaccine) |
Yes |
Yes |
Yes |
Not needed |
|
23vPPV (23-valent pneumococcal polysaccharide vaccine) |
No |
No |
No |
Yes (after 13vPCV) |
|
Varicella vaccine |
No |
No |
No |
Yes (2 doses separated by a minimum interval of 4 weeks; see comments) |
Seronegative people should receive 2 doses of varicella vaccine if they:
It is not recommended to check serology after vaccination. |
Sources: Tomblyn et al,24 Ljungman et al,25 Kumar et al,32 Cordonnier et al,33 Meisel et al,34 Centers for Disease Control and Prevention,35 Ljungman et al36
Definitions
- HSCT
- haematopoietic stem cell transplant
- DTPa
- diphtheria-tetanus-acellular pertussis vaccine
- dTpa
- diphtheria-tetanus-acellular pertussis vaccine, reduced antigen content formulation
- dT
- diphtheria-tetanus vaccine for use in adults
- IPV
- inactivated poliomyelitis vaccine
- MMR
- measles-mumps-rubella
- 13vPCV
- 13-valent pneumococcal conjugate vaccine
- 23vPPV
- 23-valent pneumococcal polysaccharide vaccine
Printed content may be out of date. For up to date information, always refer to the digital version: https://immunisationhandbook.health.gov.au/resources/handbook-tables/table-recommendations-for-revaccination-after-haematopoietic-stem-cell.