This table assumes that the person has no other factors that contribute to their being immunocompromised (such as an underlying medical condition or use of other immunosuppressive medicines).

Vaccine recipient

Prednisone-equivalent dose

Duration of therapy

Potential timing of vaccination

Adolescents aged ≥16 years and adults

<20 mg per day

Any duration

Any time during therapy

≥20 mg per day

<14 days

Immunise 1  month before starting corticosteroids or any time after stopping corticosteroids.

≥20 mg per day

≥14 days

Immunise 1  month before starting corticosteroids or at least 1 month after stopping corticosteroids.

Children and adolescents aged <16 years, weight ≤10 kg

<1 mg/kg per day

<30 days

Any time during therapy

<2 mg/kg per day

<14 days

Any time during therapy

<2 mg/kg per day

14–28 days

Immunise 1  month before starting corticosteroids or at least 1 month after stopping corticosteroids. Alternatively, the person may be able to receive live vaccines at any time during therapy, but only after seeking expert advice.

≥2 mg/kg per day

<14 days

Immunise 1  month before starting corticosteroids or any time after stopping corticosteroids.

≥2 mg/kg per day

Between 14 days and 28 days

Immunise 1  month before starting corticosteroids or at least 1 month after stopping corticosteroids.

Children and adolescents aged <16 years, weight ≥10 kg

<10 mg per day

<28 days

Any time during therapy

<20 mg per day

<14 days

Any time during therapy

<20 mg per day

14–28 days

Immunise 1 month before starting corticosteroids or at least 1 month after stopping corticosteroids. Alternatively, the person may be able to receive live vaccines at any time during therapy, but only after seeking expert advice.

≥20 mg/kg per day

<14 days

Immunise 1  month before starting corticosteroids or any time after stopping corticosteroids.

≥20 mg/kg per day

14–28 days

Immunise 1  month before starting corticosteroids or at least 1 month after stopping corticosteroids.

Children and adolescents aged <16 years, any weight

Any dose

>28 days

Immunise 1  month before starting corticosteroids or at least 1 month after stopping corticosteroids.

Last updated: 
5 June 2018
Last reviewed: 
5 June 2018