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Table. Unvaccinated people: post-exposure rabies prophylaxis based on immune status and exposure category

Immune status Exposure category HRIG Dose 1 (day 0) Dose 2 (day 3) Dose 3 (day 7) Dose 4 (day 14) Dose 5 (day 28)
Immunocompetent Category II terrestrial animals Not needed Yes Yes Yes Yes Not needed
Category II bats and any category III Yes Yes Yes Yes Yes Not needed
Mildly or moderately immunocompromised Any category II or III Yes Yes Yes Yes Yes Yes
Severely immunocompromised Any category II or III Yes Yes Yes Yes Yes Yes

HRIG = human rabies immunoglobulin

Deviations of a few days from this schedule are probably unimportant.27

For defining the level of immunocompromise, see Definitions and Table. Types of medical conditions and immunosuppressive therapy and associated levels of immunocompromise in Vaccination for people who are immunocompromised.
Related diseases
Rabies and other lyssaviruses

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