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Table. Conditions associated with increased risk of severe RSV disease in infants and young children

Risk category Details or specific conditions
Preterm birth
  • Born <32 weeks gestational age
Cardiac disease
  • Haemodynamically significant congenital heart disease
Significant immunosuppression (individual conditions listed and those that are similar based on clinical judgement)

Examples include:

  • Malignancy
  • Solid organ transplant
  • Haematopoietic stem cell transplant
  • Inborn errors of immunity associated with T cell or combined immunodeficiency, such as severe combined immunodeficiency (SCID)
Chronic respiratory disease
  • Chronic lung disease requiring ongoing oxygen or respiratory support
  • Cystic fibrosis with severe lung disease or weight for length <10th percentile
Neurological conditions that impair respiratory function (individual conditions listed and those that are similar based on clinical judgement)

Examples include:

  • Congenital, hereditary, or degenerative central nervous system disorders
  • Cerebral Palsy
  • Brain or spinal cord conditions affecting respiratory control / function
  • Neuromuscular disorders
  • Conditions with impaired swallowing/coughing or with aspiration risk
Chromosomal abnormality 
  • Trisomy 21 or another genetic condition that increases the risk of severe RSV disease

Page history

Last updated
Last reviewed
Related diseases
Respiratory syncytial virus (RSV)

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