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Table. Specified medical conditions associated with increased risk of influenza disease and severe outcomes

These examples are not exhaustive, and providers may include people with conditions similar to those listed below based on clinical judgement.

Conditions Example medical conditions NIP funded
Cardiac disease
  • Congenital heart disease
  • Congestive heart failure
  • Coronary artery disease
 Yes
Chronic respiratory condition
  • Suppurative lung disease
  • Bronchiectasis
  • Cystic fibrosis
  • Chronic obstructive pulmonary disease
  • Chronic emphysema
  • Severe asthma (requiring frequent medical consultations or the use of multiple medications)
 Yes
Immunocompromising condition
  • HIV infection
  • Malignancy
  • Immunocompromise due to disease or treatment
  • Asplenia or splenic dysfunction
  • Solid organ transplant
  • Haematopoietic stem cell transplant
  • CAR T-cell therapy
 Yes
Haematological disorder
  • Sickle cell disease or other haemoglobinopathies
 Yes
Chronic metabolic disorder
  • Type 1 or 2 diabetes
  • Amino acid disorders
  • Carbohydrate disorders
  • Cholesterol biosynthesis disorders
  • Fatty acid oxidation defects
  • Lactic acidosis
  • Mitochondrial disorders
  • Organic acid disorders
  • Urea cycle disorders
  • Vitamin/cofactor disorders
  • Porphyrias
 Yes
Chronic kidney disease
  • Chronic renal impairment – eGFR <30 mL/min (stage 4 or 5 disease)
 Yes
Chronic neurological condition
  • Hereditary and degenerative CNS diseases
  • Seizure disorders
  • Spinal cord injuries
  • Neuromuscular disorders
  • Conditions which impair respiratory or airway function
 Yes
Long-term aspirin therapy in children aged 5 to 10 years   Yes
Chronic liver disease
  • Conditions with progressive deterioration of liver function for more than 6 months including cirrhosis and other advanced liver diseases
 No
Obesity
  • Body mass index ≥30 kg per m2
 No
Chromosomal abnormality
  • Trisomy 21 or another chromosomal abnormality that increases the risk of severe disease
 No
Harmful use of alcohol   No

Page history

Last updated
Last reviewed
Related diseases
Influenza (flu)
Related chapters
Vaccination for special risk groups

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