You are here Home Resources Handbook tables Handbook tables List. Specified medical conditions associated with increased risk of invasive meningococcal disease Listen Print Share Twitter Facebook Email Conditions defects in, or deficiency of, complement components, including factor H, factor D or properdin deficiency current or future treatment with eculizumab (a monoclonal antibody directed against complement component C5) functional or anatomical asplenia, including sickle cell disease or other haemoglobinopathies, and congenital or acquired asplenia HIV, regardless of disease stage or CD4+ cell count haematopoietic stem cell transplant Page history Last updated 5 June 2018 Last reviewed 5 June 2018 Is there anything wrong with this page? Help us improve the Australian Immunisation Handbook What you were doing? (required) What went wrong? (required) Leave this field blank