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Table. Conditions associated with increased risk of severe RSV disease in infants and young children

Risk category	Details or specific conditions
Preterm birth	Born <32 weeks gestational age
Cardiac disease	Haemodynamically significant congenital heart disease
Significant immunosuppression (individual conditions listed and those that are similar based on clinical judgement)	Examples include: Malignancy Solid organ transplant Haematopoietic stem cell transplant Inborn errors of immunity associated with T cell or combined immunodeficiency, such as severe combined immunodeficiency (SCID)
Chronic respiratory disease	Chronic lung disease requiring ongoing oxygen or respiratory support Cystic fibrosis with severe lung disease or weight for length <10th percentile
Neurological conditions that impair respiratory function (individual conditions listed and those that are similar based on clinical judgement)	Examples include: Congenital, hereditary, or degenerative central nervous system disorders Cerebral Palsy Brain or spinal cord conditions affecting respiratory control / function Neuromuscular disorders Conditions with impaired swallowing/coughing or with aspiration risk
Chromosomal abnormality	Trisomy 21 or another genetic condition that increases the risk of severe RSV disease

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Last updated

31 July 2025

Last reviewed

31 July 2025

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