Table. Methods for dose extraction
Methods 1 and 2 are preferred over method 3 since they may reduce the risk of local reactions by avoiding vaccine coating the exterior of the administration needle.
| Method 1 | Method 2 | Method 3 | |
|---|---|---|---|
| Step | To extract a single dose and store the rest of the contents in the vial** | To extract multiple doses using separate drawing up and administration needles | To extract multiple doses using administration needles to draw up each dose |
| A |
Attach a sterile drawing up needle to a sterile syringe. Insert the needle through the bung into the vial. Use a 45° angle and keep the bevel of the needle up. |
Attach a sterile drawing up needle to a sterile syringe. Insert the needle through the bung into the vial. Use a 45° angle and keep the bevel of the needle up. |
Attach a sterile administration needle to a sterile syringe. Insert the needle through the bung into the vial. Use a 45° angle and keep the bevel of the needle up. |
| B |
Draw up a single dose. Do not touch the shaft of the needle. Avoid moving the needle in and out of the vial. |
Draw up a single dose. Do not touch the shaft of the needle. Avoid moving the needle in and out of the vial. |
Draw up a single dose. Do not touch the shaft of the needle. Avoid moving the needle in and out of the vial. |
| C |
Remove the filled syringe with the drawing up needle attached. Do not leave the drawing up needle in the bung. Avoid touching the top of the vial. |
Remove the filled syringe from the drawing up needle and leave the drawing up needle in the bung. Avoid touching the top of the vial. |
Remove the filled syringe with the needle attached. Avoid touching the top of the vial. |
| D |
Detach the filled syringe from the drawing up needle. Attach a new sterile injection needle. |
Detach the filled syringe and attach a new sterile injection needle to it. Immediately attach a new sterile syringe to the drawing up needle to draw up the next dose. Attach a new sterile injection needle to each filled syringe. Repeat for all doses. |
If doses will not be administered immediately, re-sheath the needle using safe aseptic technique. Repeat for all doses. |
| E | Administer the dose(s) as soon as possible | Administer the dose(s) as soon as possible | Administer the dose(s) as soon as possible |
| F | N/A |
Doses drawn up into a syringe should be used within 1 hour if kept at room temperature, or within 6 hours if stored at 2–8°C. Store in a clean container clearly labelled with:
Discard any filled syringe where there is suspicion of contamination or a sterility breach. |
Doses drawn up into a syringe should be used within 1 hour if kept at room temperature, or within 6 hours if stored at 2–8°C. Store in a clean container clearly labelled with:
Discard any filled syringe where there is suspicion of contamination or a sterility breach. |