Table. Vaccines that are contraindicated in pregnancy: live attenuated vaccines
Vaccine | Recommendation | Comments |
---|---|---|
BCG (bacille Calmette–Guérin) (live attenuated bacterial vaccine) | Contraindicated | The risk is only hypothetical. BCG vaccine has not been shown to cause fetal damage.35 |
Oral typhoid (live attenuated bacterial vaccine) | Contraindicated | No data are available on the safety of oral typhoid vaccine in pregnant women. However, because of the theoretical risk of using a live attenuated vaccine, pregnant women should receive inactivated typhoid Vi polysaccharide vaccine instead36 (see Table. Vaccines that are not routinely recommended in pregnancy: inactivated bacterial vaccines). |
Japanese encephalitis (Imojev) (live attenuated viral vaccine) | Contraindicated | The risk is only hypothetical. No data are available about using Imojev vaccine in pregnant or breastfeeding women. Women of child-bearing age should avoid pregnancy for 28 days after vaccination. |
MMR (measles-mumps-rubella) or MMRV (measles-mumps-rubella-varicella) (live attenuated viral vaccines) | Contraindicated |
|
Rotavirus (live attenuated viral vaccine) | Contraindicated | Rotavirus vaccines are not registered or recommended for use in adolescents or adults. |
Varicella (live attenuated viral vaccine) | Contraindicated | The risk is only hypothetical. Newborns of women who have inadvertently been given varicella vaccine in early pregnancy have not had congenital varicella syndrome.40 Women of child-bearing age should avoid pregnancy for 28 days after vaccination. |
Zoster (live attenuated viral vaccine) | Contraindicated | The risk is only hypothetical. Women of child-bearing age are unlikely to be eligible for vaccination, because zoster vaccine is registered for use in people ≥50 years of age. If women of child-bearing age have inadvertently been given zoster vaccine, they should avoid pregnancy for 28 days afterwards. |
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