Serology

Skin test

Interpretation and action

Positive antibody test (according to diagnostic laboratory criteria):

  • complement fixation (CF) antibody–positive, or
  • immunofluorescent antibody (IFA)–positive, or
  • enzyme immunoassay (EIA)–positive

Any skin test result

Sensitised: do not vaccinate

Equivocal antibody test (according to diagnostic laboratory criteria):

  • CF antibody equivocal, or
  • IFA equivocal, or
  • EIA equivocal

Positive (induration)

Sensitised: do not vaccinate

Borderline (induration just palpable) or negative (no induration)

Indeterminate (see Managing people with indeterminate test results)

Negative antibody test (according to diagnostic laboratory criteria):

  • CF antibody–negative, or
  • IFA-negative, or
  • EIA-negative

Positive

Sensitised: do not vaccinate

Borderline

Indeterminate (see Managing people with indeterminate test results)

Negative

Non-immune: vaccinate

Source: Modified from Marmion1

Last updated: 
5 June 2018
Last reviewed: 
5 June 2018

Definitions

EIA
enzyme immunoassay