Table. Recommended doses and schedules for combination hepatitis A and hepatitis B vaccines
| Vaccine | Age of vaccine recipient (years) | Dose (hepatitis A virus antigen) | Volume per dose (mL) | No. doses | Vaccination schedule | Notes |
|---|---|---|---|---|---|---|
| Twinrix Junior (360/10) | 1 to <16 | 360 ELISA U | 0.5 | 3 |
1st dose: day 0 (day of vaccination) 2nd dose: 1 month after 1st dose 3rd dose: 6 months after 1st dose |
None |
| Twinrix (720/20) | 1 to <16 | 720 ELISA U | 1.0 | 2 |
1st dose: day 0 (day of vaccination) 2nd dose: 6–12 months after 1st dose |
Do not use this schedule for people who need rapid protection against hepatitis B (eg a close contact of a person with chronic hepatitis B) |
| Twinrix (720/20) | ≥16 | 720 ELISA U | 1.0 | 3 |
1st dose: day 0 (day of vaccination) 2nd dose: 1 month after 1st dose 3rd dose: 6 months after 1st dose |
None |
| Twinrix (720/20) | ≥16 | 720 ELISA U | 1.0 | 4 |
1st dose: day 0 (day of vaccination) 2nd dose: 7 days after 1st dose 3rd dose: 21 days after 1st dose 4th dose: 12 months after 1st dose |
Only use this accelerated schedule if there is very limited time before travel to either moderately or highly endemic regions. See also Table. Accelerated hepatitis B vaccination schedules for people with imminent risk of exposure |
For more details on combination hepatitis A/hepatitis B vaccines and schedules, see Hepatitis B.
Last updated:
7 June 2018
Last reviewed:
7 June 2018
Definitions
- ELISA
- enzyme-linked immunosorbent assay
Printed content may be out of date. For up to date information, always refer to the digital version: https://immunisationhandbook.health.gov.au/resources/handbook-tables/table-recommended-doses-and-schedules-for-combination-hepatitis-a-and.