Table. Recommended vaccines for people before and after a solid organ transplant
The recommendations in this table are built on the principle that, where possible, children and adults should complete an age-appropriate vaccination schedule for all vaccines before transplantation. If this has not occurred, the person should receive additional vaccine doses before transplantation, if possible. Some additional vaccine doses are also recommended after transplantation (see ‘Comments’ column).
Vaccine | Before transplantation | After transplantation, (if full vaccine course not given beforehand) | Comments |
---|---|---|---|
DTPa (diphtheria-tetanus-pertussis)–containing vaccine for children <10 years of age and dTpa for those ≥10 years of age | Yes | Yes |
|
Hib (Haemophilus influenzae type b) vaccine | Yes (for children); not indicated for adults | Yes (for children); not indicated for adults |
|
Hepatitis A vaccine | Yes, if seronegative (see comments) | Yes, if seronegative (see comments) | Recommended for:
|
Hepatitis B vaccine | Yes, if seronegative (see comments) | Yes, if seronegative (see comments) |
|
9vHPV (9-valent human papillomavirus vaccine | Yes | Yes |
|
IPV (inactivated poliovirus) vaccine | Yes | Yes |
|
Influenza vaccine | Yes (1 dose every year for people ≥6 months of age) | Yes (2 doses in 1st year after transplant, then 1 dose every year after that) |
|
MenB (meningococcal B) vaccine | Yes, if at risk due to age or other defined risk factors (see comments) | Yes, if at risk due to age or other defined risk factors (see comments) |
|
MenACWY (quadrivalent meningococcal conjugate) vaccine | Yes | Yes |
|
MMR (measles-mumps-rubella) vaccine | Yes (at least 1 month before transplantation, if possible) | Contraindicated |
|
PCV (pneumococcal conjugate vaccine) - 13vPCV, 15vPCV [if ≥18 years of age] or 20vPCV [if ≥18 years of age] | Yes | Yes |
|
23vPPV (23-valent pneumococcal polysaccharide vaccine) | Yes (2–12 months after a dose of PCV (pneumococcal conjugate vaccine [13vPCV, 15vPCV or 20vPCV])) | Yes (2–12 months after a dose of PCV (13vPCV, 15vPCV or 20vPCV) | |
Varicella vaccine | Yes, (at least 1 month before transplantation, if possible) | Contraindicated |
|
Recombinant zoster vaccine (Shingrix) | Yes (complete 2-dose schedule at least 1 month before transplantation, if possible) | Yes |
|
Source: Danzinger-Isakov et al,22 Centers for Disease Control and Prevention23 |
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